Art & Culture
- Judicial Appointments in India, Executive vs Collegium
- What is Vacation Bench of Indian Supreme Court?
- State Funding of Elections
- International Religious Freedom 2019 Report
- Election Commission invokes Article 324 in West Bengal
- Difference between exit poll and opinion poll
- Madras High Court verdict on Puducherry LG Kiran Bedi
- Zero Pendency Courts Project
- ECI & Dissenting opinion controversy
Governance & Social Justice
- Supreme Court upholds Karnataka law for SC ST reservation in promotions
- Under 5 mortality & low birth weight, Analysis of Lancet Global Health journal
- US public healthcare system
- Women Workforce Participation, Issues faced by Working Women in India
- What are Small Water Enterprises?
- Cancer-causing substance found in Johnson & Johnson’s
- Age of consent & age gap under POCSO Act
- Sub-categorisation within OBCs
- Booming Population of Africa, Can Africa reap benefits of Demographic Dividend?
- Developments in Indo Pacific Region
- Joint Comprehensive Plan of Action 2015 explained
- Pakistan to Accept $6 Billion Bailout From IMF
- USA ends waiver for India on Iran Oil
- What is US Executive Privilege?
- Presidential Impeachment in the USA
- Belt and Road forum,2019
- India re-elected as observer at Arctic Council
- US Iran Tension
- India Cuts Communication with UN Human Rights
- Russia’s Sovereign Internet law
- Narendra Modi Swearing in Ceremony
- Sri Lanka signs Port Deal with India and Japan
- China’s Rare Earth Minerals
- US removes India from Currency Monitoring List
- Banking crisis in India, How bad is Non Performing Asset issue?
- Boosting Private Investment in Economy
- Economic Slowdown in various sectors
- India US Trade Dispute, Is India a Tariff King?
- India USA pact to check tax evasion by MNCs
- PepsiCo vs Potato farmers controversy
- Record GST Collections, Rs. 1.13 trillion collected in April
- Rise in Foreign Exchange Reserve of India
- SBI links interest rate of large Savings Accounts to Repo Rate
- SEBI fines NSE over unfair broker access
- Trade Policy of India, How India can mitigate Global uncertainty?
- What are PSU Telecos & their issues? Should government shutdown BSNL & MTNL?
- What is Phased Manufacturing Programme?
- What is Seed Sovereignty? PepsiCo Vs Gujarat Potato Farmers Controversy
- Why India needs a dedicated Industrial Policy?
- Why India needs a new Poultry Policy?
- WTO Appellate Body Dispute Controversy
- Dollar Rupee Swap tool of RBI
- National Anti Profiteering Authority how it works?
- Tourism boost in India, Impact of Tourism on GDP
- Urban Development Schemes in India
- US trade order bending Global trading system
- What are Social Impact Bonds?
- Is India’s GDP data accurate?
- Middle income trap
- Ban on Chinese milk products in India
- Analysis of Draft Rules for Poultry Farming
- Economic Priorities for Modi 2.0 Government
- RBI draft Liquidity Risk Management Framework for NBFCs
- SEBI panel bats to ease FPI regulations
- USA bans Huawei
- What is Regulatory Sandbox?
Defence & Security
- Gadchiroli Naxal Attack, Is India fully prepared to eliminate Naxalism?
- Government extends ban on LTTE for another 5 years
- India Signs ‘Christchurch Call to Action’ Initiative
- White House bats for declaring Muslim Brotherhood as a Terrorist Organisation
- 2019 Sri Lanka Easter bombings
- ISIS influence in India
- Designation of Masood Azhar as global terrorist
- ISIS in Jammu & Kasmir
- Influence of Islamic State in India
- Human Rights Violations in J&K
- What is Skimming? Can ATM steal users personal data?
- Kashmir’s Most Wanted Militant Zakir Musa Killed
Science & Technology
- India gets its First Apache Guardian Attack Helicopter
- Asteroid Apophis will flyby Earth
- Blockchains for Internet of Things
- ISRO’s 5 satellites saved many lives from Cyclone Fani
- Made In India Aerial Target Drone ABHYAS DRDO
- NASA Dart Mission क्या है ? Asteroid Impact Mission of NASA
- Project Blue Moon क्या है? Know all about Jeff Bezos’ mission
- Project MANAV: Human Atlas Initiative क्या है?
- Radar Controversy Explained
- Scorpene Class Submarine INS Vela Launched
- World’s first Malaria Vaccine
- Economic Impacts of Antimicrobial Resistance report by IACG
- Monkey pox infection
- India to buy kamov 31 helicopter from Russia
- Indian scientists discover how serotonin helps brain cells cope with stress
- Genetic study on people of Lakshadweep Islands
- DRDO successfully test fires AKASH MK-1S missile
- Facial Recognition Technology how it works, What are its Pros & Cons?
- Indian Airforce to Use Biofuels
- Kilogram’s New Definition
- RISAT 2B Earth Observation Satellite launched by ISRO
- UN report- One million species at risk of extinction
- Indonesia will move its capital
- Antarctica’s Emperor Penguin population declines
- Ross Ice Shelf
- Chinese ban causes re-routing of plastic waste
- Hangul or Kashmir Stag’s rapid population decline
- Indian bullfrogs take to invasive behavior early in Andaman
- Ishad Mango Facing a Threat In Its Homeland
- Lakshadweep recruits Barn Owls to fight rodent menace
- Sunscreen Killing Coral Reefs?
- Yeti footprints spotted on Himalaya claims Army
- India, China lead global greening effort
- Herbivore census in Gujarat’s Gir forest
- Karnataka declares Bukkapatna as 2nd Chinkara Wildlife Sanctuary
- Do ‘Russian poplar’ seeds cause May illness in Kashmir?
Spice of the Month
Tag: GS 3 || Science & Technology || Health & Medicine || Diseases
Why in news?
- Malawi will be undertaking large scale pilot tests for the world’s most advanced experimental malaria vaccine in a bid to prevent the disease.
- The vaccine has been recommended by WHO for pilot introduction in selected areas of 3 African countries – Ghana, Kenya and Malawi.
- Parasitic disease: Malaria is a potentially life-threatening parasitic disease caused by the parasites Plasmodium viviax (P.vivax), Plasmodium falciparum (P.falciparum), Plasmodium malariae (P.malariae), and Plasmodium ovale (P.ovale), transmitted by the female Anopheles mosquito.
- Trigger immune system: According to a description from PATH’s Malaria Vaccine Initiative (MVI), RTS,S aims to trigger the immune system to defend against the first stages of malaria when the Plasmodium falciparum parasite enters the human host’s bloodstream through a mosquito bite and infects liver cells.
- The vaccine is designed to prevent the parasite from infecting the liver, where it can mature, multiply, re-enter the bloodstream, and infect red blood cells, which can lead to disease symptoms.
- Developed by GlaxoSmithKline (GSK): The vaccine has been developed by GSK — the company is donating about 10 million doses of the product for the pilot.
- It was created in 1987 by GSK, and was subsequently developed with support from the Bill and Melinda Gates Foundation.
- In 2014, the vaccine cleared phase III clinical trials which certified that it was both effective and safe for use in humans.
- The World Health Organisation issued a statement welcoming a pilot project in Malawi of administering a malaria vaccine to children below the age of 2 years.
- Selected countries: A total 3,60,000 children across three African countries — Malawi, Ghana and Kenya — will be covered every year with the vaccine.
- WHO will review results: Once the pilots have been completed, the WHO will review the results and come out with its recommendations for the use of the vaccine.
- World’s leading killer: Malaria, according to the WHO, remains one of the world’s leading killers, claiming the life of one child every two minutes.
- Most of these deaths are in Africa, where more than 2,50,000 children die from the disease every year.
- Children under the age of 5 are at greatest risk from its life-threatening complications.
- The vaccine has taken three decades to come to fruition, and is the first one ever against a disease that kills 4,35,000 people a year, most of them children.
- India ranks high in the list of countries worst affected by the mosquito-borne disease.
- Serious malaria burden: India ranks very high in the list of countries with a serious malaria burden.
- In 2018, 3,99,134 cases of malaria and 85 deaths due to the disease were reported in the country, according to data from the National Vector Borne Disease Control Programme.
- Six states — Odisha (40%), Chhattisgarh (20%), Jharkhand (20%), Meghalaya, Arunachal Pradesh, and Mizoram (5-7%) — bear the brunt of malaria in India.
- These states, along with the tribal areas of Maharashtra and Madhya Pradesh, account for 90% of India’s malaria burden.
- Questions are repeatedly asked about the veracity of the Indian data, with some reports suggesting India may be recording just 8% of the actual number of malaria cases.
- Between 60% and 80% of patients in the urban areas are treated by private doctors or health establishments, most of whom do not notify cases.
- Although malaria is a notifiable disease, it is only voluntary notification — there are no penalties for doctors or hospitals not doing so. However, there is, of late, renewed focus on case reporting.
- PATH is an international nonprofit team of innovators which advises and partners with public institutions, businesses, grassroots groups, and investors to tackle the world’s toughest global health problems, including malaria.
- PATH’s Malaria Vaccine Initiative (MVI) works with various stakeholders towards the development of a malaria vaccine.
- Examine the status of malaria in India. What is your assessment of the potential of Mosquirix – world’s first malarial vaccine in this regard?